Figure 1: Genomic region of the X chromosome containing the X;2 translocation breakpoint and TM4SF2 (Xp11.4 tetraspanin). Figure 3: Expression of TM4SF2 in the cell lines of the patient and detection ...

Reciprocal translocations are one of the most common structural chromosome abnormalities in our species and are present in one in 500 unselected newborns studied with a moderate level of banding. 1 ...

Apparently balanced reciprocal translocations are one of the most common genetic causes of male infertility. The commonly accepted underlying pathophysiological mechanism is that they impair meiosis ...

Translocation is a genetic abnormality in which part of a chromosome moves to another chromosome. Chromosomes are genetic structures within cells that hold genes. When translocation occurs, it causes ...

Leukemia is an umbrella term for multiple different cancers that form in the blood, one such member of the leukemia family being chronic myelogenous leukemia (CML). CML is caused by a chromosomal ...

Treatment-Free Survival: A Novel Outcome Measure of the Effects of Immune Checkpoint Inhibition—A Pooled Analysis of Patients With Advanced Melanoma ...

Robertsonian translocation is the most common form of chromosomal translocation in humans. It means that two chromosomes, the structures that make up a person’s DNA, join together in an abnormal way.

These images captured using high-speed atomic force microscopy, represent the snapshots of the protein substrate getting translocated through the SecYEG-SecA complex. The left image indicates the ...