Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine. Guiding iPSCs toward a target cell line has garnered much ...

Researchers studying mesenchymal stem cells (MSCs) face significant challenges with traditional endpoint assays that provide only limited snapshots of the differentiation process. The inability to ...

Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress from precursor to progeny, scientists have produced the first-ever ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

An anti-nucleolin DNA aptamer, iSN04, regulates cardiomyogenesis of murine pluripotent stem cells. Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the ...